Varaico: Literature-Extracted Genetic Variants

RPS6KA2

84 papers

RefSeq Summary

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains two non-identical kinase catalytic domains and phosphorylates various substrates, i...

Pfam Domains

Pkinaseaa 59–318UCSCProtein kinase domain

Pkinase_Caa 342–378UCSCProtein kinase C terminal domain

Pkinaseaa 415–672UCSCProtein kinase domain

Gene Aliases

HGNC Name

ribosomal protein S6 kinase A2

HGNC Alias Symbols

RSK3; HU-2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021135.6

p.R462R

c.1384C>A

Surrounding Variants

2 papers

NM_021135.6

p.L472R

c.1415T>G

1 paper

NM_021135.6

p.I446T

c.1337T>C

1 paper

NM_021135.6

p.I445N

c.1334T>A

1 paper

NM_021135.6

p.F481V

c.1441T>G

1 paper

NM_021135.6

p.L488L

c.1464G>A

1 paper

NM_021135.6

p.R500Q

c.1499G>A

2 papers

NM_021135.6

p.L513L

c.1539G>A

1 paper

NM_021135.6

p.R551Q

c.1652G>A

1 paper

NM_021135.6

p.G556C

c.1666G>T

1 paper

NM_021135.6

p.Q560Q

c.1680G>A

1 paper

NM_021135.6

p.L561R

c.1682T>G

1 paper

NM_021135.6

p.R562C

c.1684C>T