Varaico: Literature-Extracted Genetic Variants

RPS6KA2

84 papers

RefSeq Summary

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains two non-identical kinase catalytic domains and phosphorylates various substrates, i...

Pfam Domains

Pkinaseaa 59–318UCSCProtein kinase domain

Pkinase_Caa 342–378UCSCProtein kinase C terminal domain

Pkinaseaa 415–672UCSCProtein kinase domain

Gene Aliases

HGNC Name

ribosomal protein S6 kinase A2

HGNC Alias Symbols

RSK3; HU-2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021135.6

p.E188V

c.563A>T

Surrounding Variants

1 paper

NM_021135.6

p.K162Q

c.484A>C

1 paper

NM_021135.6

p.T157M

c.470C>T

1 paper

NM_021135.6

p.D193N

c.577G>A

1 paper

NM_021135.6

p.E153D

c.459G>T

1 paper

NM_021135.6

p.E153D

c.459G>C

1 paper

NM_021135.6

p.R149Q

c.446G>A

1 paper

NM_021135.6

p.D139H

c.415G>C

1 paper

NM_021135.6

p.Y135del1

c.403_405delGTA

1 paper

NM_021135.6

p.L134L

c.402C>A

1 paper

NM_021135.6

p.R110*

c.328A>T

1 paper

NM_021135.6

p.G204R

c.610G>C

1 paper

NM_021135.6

p.A209D

c.626C>A