Varaico: Literature-Extracted Genetic Variants

RPS6KA3

325 papers

RefSeq Summary

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, inc...

Pfam Domains

Pkinaseaa 68–327UCSCProtein kinase domain

Pkinase_Caa 351–387UCSCProtein kinase C terminal domain

Pkinaseaa 422–679UCSCProtein kinase domain

Gene Aliases

HGNC Name

ribosomal protein S6 kinase A3

HGNC Previous Symbols

MRX19; CLS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004586.3

p.T348_G349delFs

c.1044_1045delCC

Surrounding Variants

1 paper

NM_004586.3

p.A347_G349delFs

c.1039_1046del8

1 paper

NM_004586.3

p.K345_G349del0

c.1035_1046del12

1 paper

NM_004586.3

p.T348M

c.1043C>T

1 paper

NM_004586.3

p.K345_P351delFs

c.1034_1053del20

1 paper

NM_004586.3

p.A347fs

c.1039_1040fs

1 paper

NM_004586.3

p.A347_E352delFs

c.1039_1055del17

1 paper

NM_004586.3

p.T354fs

c.1060_1061fs

1 paper

NM_004586.3

p.Y356C

c.1067A>G

1 paper

NM_004586.3

p.D358N

c.1072G>A

1 paper

NM_004586.3

p.T362delFs

c.1086delA

1 paper

NM_004586.3

p.T365A

c.1093A>G

1 paper

NM_004586.3

p.K334E

c.1000A>G