Varaico: Literature-Extracted Genetic Variants

RPS6KA3

325 papers

RefSeq Summary

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, inc...

Pfam Domains

Pkinaseaa 68–327UCSCProtein kinase domain

Pkinase_Caa 351–387UCSCProtein kinase C terminal domain

Pkinaseaa 422–679UCSCProtein kinase domain

Gene Aliases

HGNC Name

ribosomal protein S6 kinase A3

HGNC Previous Symbols

MRX19; CLS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004586.3

p.T329A

c.985A>G

Surrounding Variants

1 paper

NM_004586.3

p.D331N

c.991G>A

1 paper

NM_004586.3

p.F326S

c.977T>C

1 paper

NM_004586.3

p.W332*

c.995G>A

1 paper

NM_004586.3

p.W332*

c.996G>A

3 papers

NM_004586.3

p.H324fs

c.970_971fs

2 papers

NM_004586.3

p.R323T

c.968G>C

5 papers

NM_004586.3

p.K322_R323delFs

c.966_967delTT

1 paper

NM_004586.3

p.R323G

c.967A>G

1 paper

NM_004586.3

p.V318D

c.953T>A

1 paper

NM_004586.3

p.A313_G314insFs

c.937_940dup4

1 paper

NM_004586.3

p.G314*

c.940G>T

1 paper

NM_004586.3

p.A313S

c.937G>T