Varaico: Literature-Extracted Genetic Variants

RPS6KA3

325 papers

RefSeq Summary

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, inc...

Pfam Domains

Pkinaseaa 68–327UCSCProtein kinase domain

Pkinase_Caa 351–387UCSCProtein kinase C terminal domain

Pkinaseaa 422–679UCSCProtein kinase domain

Gene Aliases

HGNC Name

ribosomal protein S6 kinase A3

HGNC Previous Symbols

MRX19; CLS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004586.3

p.L214insFs

c.641_642insC

Surrounding Variants

2 papers

NM_004586.3

p.G213D

c.638G>A

1 paper

NM_004586.3

p.K216E

c.646A>G

1 paper

NM_004586.3

p.E217K

c.649G>A

1 paper

NM_004586.3

p.S215_K216delFs

c.645_648del4

4 papers

NM_004586.3

p.D211Splc

c.632-1G>T

1 paper

NM_004586.3

p.D211H

c.631G>C

1 paper

NM_004586.3

p.D211Splc

c.632-1G>A

1 paper

NM_004586.3

p.D211Splc

c.632-2A>G

1 paper

NM_004586.3

p.K224*

c.670A>T

4 papers

NM_004586.3

p.A225V

c.674C>T

1 paper

NM_004586.3

p.Y226N

c.676T>A

13 papers

NM_004586.3

p.S227A

c.679T>G