Varaico: Literature-Extracted Genetic Variants

RPS6KA3

325 papers

RefSeq Summary

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, inc...

Pfam Domains

Pkinaseaa 68–327UCSCProtein kinase domain

Pkinase_Caa 351–387UCSCProtein kinase C terminal domain

Pkinaseaa 422–679UCSCProtein kinase domain

Gene Aliases

HGNC Name

ribosomal protein S6 kinase A3

HGNC Previous Symbols

MRX19; CLS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004586.3

p.D92N

c.274G>A

Surrounding Variants

1 paper

NM_004586.3

p.A93A

c.279T>G

2 papers

NM_004586.3

p.A93delFs

c.279delA

2 papers

NM_004586.3

p.A93_R94del1

c.278_280delTAG

1 paper

NM_004586.3

p.S89*

c.266C>G

1 paper

NM_004586.3

p.S89*

c.266C>A

1 paper

NM_004586.3

p.S89fs

c.265_266fs

1 paper

NM_004586.3

p.I88insFs

c.263dupT

1 paper

NM_004586.3

p.I88fs

c.262_263fs

6 papers

NM_004586.3

p.I88insFs

c.262_263insA

1 paper

NM_004586.3

p.K86delFs

c.256delT

2 papers

NM_004586.3

p.Y97C

c.290A>G

2 papers

NM_004586.3

p.Y97*

c.291T>G