Varaico: Literature-Extracted Genetic Variants

RPS6KA3

325 papers

RefSeq Summary

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, inc...

Pfam Domains

Pkinaseaa 68–327UCSCProtein kinase domain

Pkinase_Caa 351–387UCSCProtein kinase C terminal domain

Pkinaseaa 422–679UCSCProtein kinase domain

Gene Aliases

HGNC Name

ribosomal protein S6 kinase A3

HGNC Previous Symbols

MRX19; CLS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_004586.3

p.G80R

c.238G>A

Surrounding Variants

2 papers

NM_004586.3

p.G80R

c.238G>C

1 paper

NM_004586.3

p.K81*

c.241A>T

1 paper

NM_004586.3

p.K81N

c.243G>T

1 paper

NM_004586.3

p.K81N

c.243G>C

1 paper

NM_004586.3

p.G77R

c.229G>C

1 paper

NM_004586.3

p.G77R

c.229G>A

7 papers

NM_004586.3

p.G75V

c.224G>T

1 paper

NM_004586.3

p.L74F

c.222A>T

1 paper

NM_004586.3

p.L74F

c.222A>C

1 paper

NM_004586.3

p.E69A

c.206A>C

1 paper

NM_004586.3

p.E69*

c.205G>T

1 paper

NM_004586.3

p.K81_V82Splc

c.243+28G>A