Varaico: Literature-Extracted Genetic Variants

RPS6KA3

325 papers

RefSeq Summary

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, inc...

Pfam Domains

Pkinaseaa 68–327UCSCProtein kinase domain

Pkinase_Caa 351–387UCSCProtein kinase C terminal domain

Pkinaseaa 422–679UCSCProtein kinase domain

Gene Aliases

HGNC Name

ribosomal protein S6 kinase A3

HGNC Previous Symbols

MRX19; CLS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_004586.3

p.T53_H55delFs

c.158_164del7

Surrounding Variants

1 paper

NM_004586.3

p.H54insFs

c.161dupA

1 paper

NM_004586.3

p.H54N

c.160C>A

1 paper

NM_004586.3

p.E58fs

c.172_173fs

1 paper

NM_004586.3

p.G59*

c.175G>T

1 paper

NM_004586.3

p.E44delFs

c.130delC

1 paper

NM_004586.3

p.E44fs

c.130_131fs

4 papers

NM_004586.3

p.F68L

c.202T>C

1 paper

NM_004586.3

p.E43G

c.128A>G

3 papers

NM_004586.3

p.F68C

c.203T>G

4 papers

NM_004586.3

p.F68L

c.204T>G

4 papers

NM_004586.3

p.F68L

c.204T>A

1 paper

NM_004586.3

p.E69*

c.205G>T