Varaico: Literature-Extracted Genetic Variants

RPS6KA4

121 papers

RefSeq Summary

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, inc...

Pfam Domains

Pkinaseaa 33–301UCSCProtein kinase domain

Pkinase_Caa 322–361UCSCProtein kinase C terminal domain

Pkinaseaa 412–674UCSCProtein kinase domain

Gene Aliases

HGNC Name

ribosomal protein S6 kinase A4

HGNC Alias Symbols

RSK-B; MSK2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003942.3

p.K65R

c.194A>G

Surrounding Variants

1 paper

NM_003942.3

p.A63T

c.187G>A

1 paper

NM_003942.3

p.A76T

c.226G>A

1 paper

NM_003942.3

p.T78R

c.233C>G

1 paper

NM_003942.3

p.F48F

c.144C>T

1 paper

NM_003942.3

p.Y44H

c.130T>C

1 paper

NM_003942.3

p.T100M

c.299C>T

1 paper

NM_003942.3

p.G120G

c.360C>T

2 papers

NM_003942.3

p.Q129*

c.385C>T

1 paper

NM_003942.3

p.G143V

c.428G>T

1 paper

NM_003942.3

p.I145V

c.433A>G

1 paper

NM_003942.3

p.T188M

c.563C>T

2 papers

NM_003942.3

p.R193Q

c.578G>A