Varaico: Literature-Extracted Genetic Variants

RPS6KA4

121 papers

RefSeq Summary

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, inc...

Pfam Domains

Pkinaseaa 33–301UCSCProtein kinase domain

Pkinase_Caa 322–361UCSCProtein kinase C terminal domain

Pkinaseaa 412–674UCSCProtein kinase domain

Gene Aliases

HGNC Name

ribosomal protein S6 kinase A4

HGNC Alias Symbols

RSK-B; MSK2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003942.3

p.E471K

c.1411G>A

Surrounding Variants

1 paper

NM_003942.3

p.E471V

c.1412A>T

1 paper

NM_003942.3

p.V466M

c.1396G>A

1 paper

NM_003942.3

p.V466L

c.1396G>C

1 paper

NM_003942.3

p.V466L

c.1396G>T

1 paper

NM_003942.3

p.N465T

c.1394A>C

2 papers

NM_003942.3

p.C460F

c.1379G>T

1 paper

NM_003942.3

p.E453K

c.1357G>A

1 paper

NM_003942.3

p.R445Splc

c.1334+39G>A

1 paper

NM_003942.3

p.R445W

c.1333A>T

1 paper

NM_003942.3

p.L442P

c.1325T>C

1 paper

NM_003942.3

p.R431R

c.1293C>T

1 paper

NM_003942.3

p.C428C

c.1284C>T