Varaico: Literature-Extracted Genetic Variants

RPS6KA4

121 papers

RefSeq Summary

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, inc...

Pfam Domains

Pkinaseaa 33–301UCSCProtein kinase domain

Pkinase_Caa 322–361UCSCProtein kinase C terminal domain

Pkinaseaa 412–674UCSCProtein kinase domain

Gene Aliases

HGNC Name

ribosomal protein S6 kinase A4

HGNC Alias Symbols

RSK-B; MSK2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003942.3

p.D551N

c.1651G>A

Surrounding Variants

1 paper

NM_003942.3

p.R556W

c.1666C>T

1 paper

NM_003942.3

p.T542S

c.1624A>T

1 paper

NM_003942.3

p.Q560E

c.1678C>G

1 paper

NM_003942.3

p.A539S

c.1615G>T

1 paper

NM_003942.3

p.Q567E

c.1699C>G

1 paper

NM_003942.3

p.A582E

c.1745C>A

1 paper

NM_003942.3

p.D591N

c.1771G>A

1 paper

NM_003942.3

p.G596D

c.1787G>A

1 paper

NM_003942.3

p.V597I

c.1789G>A

1 paper

NM_003942.3

p.L531I

c.1591C>A

1 paper

NM_003942.3

p.R529H

c.1586G>A

1 paper

NM_003942.3

p.R529C

c.1585C>T