Varaico: Literature-Extracted Genetic Variants

RPS6KA4

121 papers

RefSeq Summary

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, inc...

Pfam Domains

Pkinaseaa 33–301UCSCProtein kinase domain

Pkinase_Caa 322–361UCSCProtein kinase C terminal domain

Pkinaseaa 412–674UCSCProtein kinase domain

Gene Aliases

HGNC Name

ribosomal protein S6 kinase A4

HGNC Alias Symbols

RSK-B; MSK2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003942.3

p.A704T

c.2110G>A

Surrounding Variants

1 paper

NM_003942.3

p.N703N

c.2109C>T

1 paper

NM_003942.3

p.T705_F706ins6

c.2113_2117ins18

1 paper

NM_003942.3

p.P684P

c.2052G>A

1 paper

NM_003942.3

p.S682S

c.2046G>A

1 paper

NM_003942.3

p.R680L

c.2039G>T

1 paper

NM_003942.3

p.R652Q

c.1955G>A

1 paper

NM_003942.3

p.E638G

c.1913A>G

1 paper

NM_003942.3

p.G637V

c.1910G>T

1 paper

NM_003942.3

p.G637R

c.1909G>A

1 paper

NM_003942.3

p.G637R

c.1909G>C

1 paper

NM_003942.3

p.F633L

c.1899C>A

2 papers

NM_003942.3

p.R629C

c.1885C>T