Varaico: Literature-Extracted Genetic Variants

Gene:RPS6KB1
Variant:p.M129L

RPS6KB1

318 papers

RefSeq Summary

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, c...

Pfam Domains

Pkinaseaa 91–352UCSCProtein kinase domain
Pkinase_Caa 373–413UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

ribosomal protein S6 kinase B1

HGNC Previous Symbol

STK14A

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_003161.4
p.M129L
c.385A>T
Surrounding Variants
1 paper
NM_003161.4
p.M129L
c.385A>C
2 papers
NM_003161.4
p.I130K
c.389T>A
1 paper
NM_003161.4
p.I130M
c.390A>G
1 paper
NM_003161.4
p.R132K
c.395G>A
1 paper
NM_003161.4
p.A138T
c.412G>A
1 paper
NM_003161.4
p.A138G
c.413C>G
1 paper
NM_003161.4
p.A142_E143del2
c.424_428del6
1 paper
NM_003161.4
p.A142V
c.425C>T
1 paper
NM_003161.4
p.N145S
c.434A>G
1 paper
NM_003161.4
p.V150E
c.449T>A
1 paper
NM_003161.4
p.I155I
c.465C>T
1 paper
NM_003161.4
p.D157N
c.469G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."