Varaico: Literature-Extracted Genetic Variants

RPS6KB2

174 papers

RefSeq Summary

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryoti...

Pfam Domains

Pkinaseaa 67–328UCSCProtein kinase domain

Pkinase_Caa 349–389UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

ribosomal protein S6 kinase B2

HGNC Alias Symbols

p70S6Kb; P70-BETA; STK14B; KLS; S6KB; S6Kbeta; S6Kβ

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003952.3

p.E40K

c.118G>A

Surrounding Variants

1 paper

NM_003952.3

p.L39L

c.117A>G

1 paper

NM_003952.3

p.A37G

c.110C>G

1 paper

NM_003952.3

p.A37T

c.109G>A

1 paper

NM_003952.3

p.A36A

c.108A>C

1 paper

NM_003952.3

p.L34L

c.102G>A

1 paper

NM_003952.3

p.L31L

c.93T>C

1 paper

NM_003952.3

p.D27E

c.81C>G

1 paper

NM_003952.3

p.G43_H44ins6

c.127_131ins18

1 paper

NM_003952.3

p.G43G

c.129A>C

1 paper

NM_003952.3

p.H44Y

c.130C>T

1 paper

NM_003952.3

p.H44R

c.131A>G

1 paper

NM_003952.3

p.E47K

c.139G>A