Varaico: Literature-Extracted Genetic Variants

RPS6KB2

174 papers

RefSeq Summary

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryoti...

Pfam Domains

Pkinaseaa 67–328UCSCProtein kinase domain

Pkinase_Caa 349–389UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

ribosomal protein S6 kinase B2

HGNC Alias Symbols

p70S6Kb; P70-BETA; STK14B; KLS; S6KB; S6Kbeta; S6Kβ

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003952.3

p.D112N

c.334G>A

Surrounding Variants

1 paper

NM_003952.3

p.K111E

c.331A>G

1 paper

NM_003952.3

p.A110D

c.329C>A

1 paper

NM_003952.3

p.N109S

c.326A>G

1 paper

NM_003952.3

p.R108R

c.324C>T

1 paper

NM_003952.3

p.R108P

c.323G>C

1 paper

NM_003952.3

p.I106I

c.318T>A

1 paper

NM_003952.3

p.K105N

c.315A>T

1 paper

NM_003952.3

p.A118G

c.353C>G

1 paper

NM_003952.3

p.E119K

c.355G>A

4 papers

NM_003952.3

p.R120W

c.358C>T

1 paper

NM_003952.3

p.I122I

c.366T>C

1 paper

NM_003952.3

p.I122M

c.366T>G