Varaico: Literature-Extracted Genetic Variants

RPS6KB2

174 papers

RefSeq Summary

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryoti...

Pfam Domains

Pkinaseaa 67–328UCSCProtein kinase domain

Pkinase_Caa 349–389UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

ribosomal protein S6 kinase B2

HGNC Alias Symbols

p70S6Kb; P70-BETA; STK14B; KLS; S6KB; S6Kbeta; S6Kβ

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003952.3

p.Y136C

c.407A>G

Surrounding Variants

1 paper

NM_003952.3

p.Y136Y

c.408T>C

1 paper

NM_003952.3

p.L134Q

c.401T>A

1 paper

NM_003952.3

p.E133K

c.397G>A

1 paper

NM_003952.3

p.E133*

c.397G>T

2 papers

NM_003952.3

p.V132A

c.395T>C

1 paper

NM_003952.3

p.I131T

c.392T>C

1 paper

NM_003952.3

p.G142S

c.424G>A

1 paper

NM_003952.3

p.G142C

c.424G>T

1 paper

NM_003952.3

p.F130I

c.388T>A

2 papers

NM_003952.3

p.P129H

c.386C>A

1 paper

NM_003952.3

p.H128Y

c.382C>T

1 paper

NM_003952.3

p.K127N

c.381G>C