Varaico: Literature-Extracted Genetic Variants

RPS6KB2

174 papers

RefSeq Summary

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryoti...

Pfam Domains

Pkinaseaa 67–328UCSCProtein kinase domain

Pkinase_Caa 349–389UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

ribosomal protein S6 kinase B2

HGNC Alias Symbols

p70S6Kb; P70-BETA; STK14B; KLS; S6KB; S6Kbeta; S6Kβ

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003952.3

p.F269F

c.807C>T

Surrounding Variants

1 paper

NM_003952.3

p.T270N

c.809C>A

1 paper

NM_003952.3

p.A271T

c.811G>A

8 papers

NM_003952.3

p.P267L

c.800C>T

1 paper

NM_003952.3

p.P267_F269delins

c.800_807delinsTGCCCTTT

1 paper

NM_003952.3

p.P267fs

c.799_800fs

1 paper

NM_003952.3

p.R274Q

c.821G>A

1 paper

NM_003952.3

p.K275K

c.825G>A

1 paper

NM_003952.3

p.S266_P267Splc

c.799-12C>T

1 paper

NM_003952.3

p.T277A

c.829A>G

1 paper

NM_003952.3

p.I282L

c.844A>C

2 papers

NM_003952.3

p.I282F

c.844A>T

1 paper

NM_003952.3

p.P289T

c.865C>A