Varaico: Literature-Extracted Genetic Variants

Gene:RRM2B
Variant:p.R186G

RRM2B

203 papers

RefSeq Summary

This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphate...

Pfam Domains

Ribonuc_red_smaa 41–308UCSCRibonucleotide reductase, small chain

Gene Aliases

HGNC Name

ribonucleotide reductase regulatory TP53 inducible subunit M2B

HGNC Alias Symbol

p53R2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
10 papers
NM_015713.5
p.R186G
c.556A>G
Surrounding Variants
1 paper
NM_015713.5
p.E185_V187Fs
c.554_559delinsTGTGFs
1 paper
NM_015713.5
p.G184Splc
c.551-2A>G
1 paper
NM_015713.5
p.A192T
c.574G>A
2 papers
NM_015713.5
p.A192V
c.575C>T
1 paper
NM_015713.5
p.V193E
c.578T>A
8 papers
NM_015713.5
p.E194K
c.580G>A
9 papers
NM_015713.5
p.E194G
c.581A>G
6 papers
NM_015713.5
p.G195R
c.583G>C
8 papers
NM_015713.5
p.G195R
c.583G>A
1 paper
NM_015713.5
p.G195fs
c.583_584fs
5 papers
NM_015713.5
p.G195delFs
c.584delC
1 paper
NM_015713.5
p.V196I
c.586G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."