R-spondin 3

THSD2

FLJ14440

thrombospondin, type I, domain containing 2

R-spondin 3 homolog (Xenopus laevis)

R-spondin-3

Protein with TSP type-1 repeat

Roof plate-specific spondin-3

Thrombospondin type-1 domain-containing protein 2

hPWTSR

hRspo3

This gene belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of this gene with bone mineral density and risk of fracture. This gene may be involved in tumor development. [provided by RefSeq, Jul 2013].

Varaico: Literature-Extracted Genetic Variants

RSPO3

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Symbol