Varaico: Literature-Extracted Genetic Variants

Gene:RUNX3
Variant:p.P21S

RUNX3

166 papers

RefSeq Summary

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYG...

Pfam Domains

Runtaa 55–183UCSCRunt domain
RunxIaa 316–415UCSCRunx inhibition domain

Gene Aliases

HGNC Name

RUNX family transcription factor 3

HGNC Previous Symbol

CBFA3

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004350.3
p.P21S
c.61C>T
Surrounding Variants
1 paper
NM_004350.3
p.F20S
c.59T>C
1 paper
NM_004350.3
p.A19insFs
c.56_57insC
1 paper
NM_004350.3
p.F20I
c.58T>A
1 paper
NM_004350.3
p.A19A
c.57C>A
1 paper
NM_004350.3
p.A19P
c.55G>C
2 papers
NM_004350.3
p.P18delFs
c.53delG
1 paper
NM_004350.3
p.G24C
c.70G>T
1 paper
NM_004350.3
p.G24G
c.72C>T
1 paper
NM_004350.3
p.G26S
c.76G>A
2 papers
NM_004350.3
p.P15_P16insFs
c.45_46insT
1 paper
NM_004350.3
p.G27D
c.80G>A
1 paper
NM_004350.3
p.K28K
c.84G>A
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