syndecan 2

HSPG1

fibroglycan

SYND2

CD362

heparan sulfate proteoglycan 1, cell surface-associated

syndecan proteoglycan 2

Syndecan-2

Fibroglycan

Heparan sulfate proteoglycan core protein

HSPG

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008].

Varaico: Literature-Extracted Genetic Variants

SDC2

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Symbol