Varaico: Literature-Extracted Genetic Variants

SDHA

1,054 papers

RefSeq Summary

This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is lo...

Pfam Domains

FAD_binding_2aa 63–457UCSCFAD binding domain

Succ_DH_flav_Caa 512–664UCSCFumarate reductase flavoprotein C-term

Gene Aliases

HGNC Name

succinate dehydrogenase complex flavoprotein subunit A

HGNC Previous Symbol

SDH2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004168.4

p.E61G

c.182A>G

Surrounding Variants

1 paper

NM_004168.4

p.E61V

c.182A>T

1 paper

NM_004168.4

p.F62insFs

c.184_185insTC

2 papers

NM_004168.4

p.E61delFs

c.181delG

1 paper

NM_004168.4

p.D63_V66delFs

c.188_198del11

1 paper

NM_004168.4

p.D63delFs

c.187delG

1 paper

NM_004168.4

p.D63H

c.187G>C

1 paper

NM_004168.4

p.D59A

c.176A>C

2 papers

NM_004168.4

p.D59G

c.176A>G

2 papers

NM_004168.4

p.D63G

c.188A>G

1 paper

NM_004168.4

p.D63V

c.188A>T

1 paper

NM_004168.4

p.D59H

c.175G>C

1 paper

NM_004168.4

p.A64delFs

c.190delG