Varaico: Literature-Extracted Genetic Variants

SDHB

1,345 papers

RefSeq Summary

This tumor suppressor gene encodes the iron-sulfur protein subunit of the succinate dehydrogenase (SDH) enzyme complex which plays a critical role in mitochondria. The SDH enzyme complex is composed o...

Pfam Domains

Fer2_3aa 41–144UCSC2Fe-2S iron-sulfur cluster binding domain

Fer4_17aa 167–240UCSC4Fe-4S dicluster domain

Gene Aliases

HGNC Name

succinate dehydrogenase complex iron sulfur subunit B

HGNC Previous Symbols

SDH1; SDH

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003000.3

p.Q24_A25Splc

c.72+3G>A

Surrounding Variants

4 papers

NM_003000.3

p.Q24_A25Splc

c.72+2T>G

48 papers

NM_003000.3

p.Q24_A25Splc

c.72+1G>T

2 papers

NM_003000.3

p.Q24_A25Splc

c.72+1G>C

1 paper

NM_003000.3

p.Q24_A25Splc

c.72+5G>C

10 papers

NM_003000.3

p.Q24_A25Splc

c.72+1G>A

1 paper

NM_003000.3

p.Q24_A25Splc

c.72+5G>A

1 paper

NM_003000.3

p.Q24H

c.72G>T

3 papers

NM_003000.3

p.Q24insFs

c.71dupA

1 paper

NM_003000.3

p.Q24H

c.72G>C

1 paper

NM_003000.3

p.Q24_A25Splc

c.72+7C>A

1 paper

NM_003000.3

p.Q24P

c.71A>C

4 papers

NM_003000.3

p.Q24*

c.70C>T