Varaico: Literature-Extracted Genetic Variants

SDHB

1,345 papers

RefSeq Summary

This tumor suppressor gene encodes the iron-sulfur protein subunit of the succinate dehydrogenase (SDH) enzyme complex which plays a critical role in mitochondria. The SDH enzyme complex is composed o...

Pfam Domains

Fer2_3aa 41–144UCSC2Fe-2S iron-sulfur cluster binding domain

Fer4_17aa 167–240UCSC4Fe-4S dicluster domain

Gene Aliases

HGNC Name

succinate dehydrogenase complex iron sulfur subunit B

HGNC Previous Symbols

SDH1; SDH

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003000.3

p.V4_V5insFs

c.12_13insTG

Surrounding Variants

2 papers

NM_003000.3

p.V4V

c.12G>C

1 paper

NM_003000.3

p.V4V

c.12G>A

1 paper

NM_003000.3

p.A3insFs

c.9dupG

1 paper

NM_003000.3

p.V4E

c.11T>A

1 paper

NM_003000.3

p.V5F

c.13G>T

1 paper

NM_003000.3

p.V5insFs

c.13_14insTG

1 paper

NM_003000.3

p.V5insFs

c.13_14insTA

1 paper

NM_003000.3

p.V5L

c.13G>C

2 papers

NM_003000.3

p.V5I

c.13G>A

1 paper

NM_003000.3

p.V5ins1

c.14_15insCTT

1 paper

NM_003000.3

p.V4insFs

c.12dupG

4 papers

NM_003000.3

p.V5G

c.14T>G