Varaico: Literature-Extracted Genetic Variants

Gene:SEC61A1
Variant:p.S177_T185del0

SEC61A1

83 papers

RefSeq Summary

The protein encoded by this gene belongs to the SECY/SEC61- alpha family. It appears to play a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. This...

Pfam Domains

Plug_transloconaa 1–21UCSCPlug domain of Sec61p
SecYaa 22–405UCSCSecY

Gene Aliases

HGNC Name

SEC61 translocon subunit alpha 1

HGNC Previous Name

Sec61 alpha 1 subunit (S. cerevisiae)

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_013336.4
p.S177_T185del0
c.529_555del27
Surrounding Variants
1 paper
NM_013336.4
p.G178A
c.533G>C
1 paper
NM_013336.4
p.I183F
c.547A>T
1 paper
NM_013336.4
p.Q170*
c.508C>T
12 papers
NM_013336.4
p.T185A
c.553A>G
1 paper
NM_013336.4
p.T185I
c.554C>T
1 paper
NM_013336.4
p.T190I
c.569C>T
1 paper
NM_013336.4
p.S197insFs
c.589_590ins8
1 paper
NM_013336.4
p.F156L
c.466T>C
1 paper
NM_013336.4
p.G204R
c.610G>C
1 paper
NM_013336.4
p.R205P
c.614G>C
1 paper
NM_013336.4
p.G144C
c.430G>T
1 paper
NM_013336.4
p.T134delFs
c.400delA
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