SUMO specific peptidase 7

SUMO1/sentrin specific protease 7

SUMO1/sentrin specific peptidase 7

Sentrin-specific protease 7

SUMO-1-specific protease 2

Sentrin/SUMO-specific protease SENP7

Ulp1 protease family, C-terminal catalytic domain

The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009].

Varaico: Literature-Extracted Genetic Variants

SENP7

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Names