Varaico: Literature-Extracted Genetic Variants

Gene:SERPINB4

SERPINB4

91 papers

RefSeq Summary

The protein encoded by this gene is a member of the serpin family of serine protease inhibitors. The encoded protein is highly expressed in many tumor cells and can inactivate granzyme M, an enzyme th...

Pfam Domains

Serpinaa 6–390UCSCSerpin (serine protease inhibitor)

Gene Aliases

HGNC Name

serpin family B member 4

HGNC Previous Symbol

SCCA2

Papers
RefSeq ID
Protein change
DNA change
1–12 of 110 variants
3 papers
NM_002974.4
p.N65Y
c.193A>T
3 papers
NM_002974.4
p.K111N
c.333G>T
2 papers
NM_002974.4
p.S95F
c.284C>T
2 papers
NM_002974.4
p.K111N
c.333G>C
2 papers
NM_002974.4
p.D165D
c.495T>C
2 papers
NM_002974.4
p.L174fs
c.520_521fs
2 papers
NM_002974.4
p.L174delFs
c.520delG
2 papers
NM_002974.4
p.D226N
c.676G>A
2 papers
NM_002974.4
p.E250*
c.748G>T
1 paper
NM_002974.4
p.M1insFs
c.2_3insT
1 paper
NM_002974.4
p.N2_S3insT
c.4_8ins3
1 paper
NM_002974.4
p.L4H
c.11T>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."