Varaico: Literature-Extracted Genetic Variants

Gene:SERPINE1
Variant:p.V11I

SERPINE1

988 papers

RefSeq Summary

This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an in...

Pfam Domains

Serpinaa 33–402UCSCSerpin (serine protease inhibitor)

Gene Aliases

HGNC Name

serpin family E member 1

HGNC Previous Symbols

PLANH1; PAI1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000602.5
p.V11I
c.31G>A
Surrounding Variants
1 paper
NM_000602.5
p.L10Q
c.29T>A
4 papers
NM_000602.5
p.L10P
c.29T>C
1 paper
NM_000602.5
p.L10V
c.28C>G
1 paper
NM_000602.5
p.L12V
c.34C>G
2 papers
NM_000602.5
p.G13C
c.37G>T
1 paper
NM_000602.5
p.C9R
c.25T>C
1 paper
NM_000602.5
p.C9G
c.25T>G
3 papers
NM_000602.5
p.G13D
c.38G>A
2 papers
NM_000602.5
p.G13A
c.38G>C
1 paper
NM_000602.5
p.G13V
c.38G>T
1 paper
NM_000602.5
p.T8N
c.23C>A
1 paper
NM_000602.5
p.L14M
c.40C>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."