Varaico: Literature-Extracted Genetic Variants

Gene:SERPINF2
Variant:p.Q458R

SERPINF2

130 papers

RefSeq Summary

This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper f...

Pfam Domains

Serpinaa 84–436UCSCSerpin (serine protease inhibitor)

Gene Aliases

HGNC Name

serpin family F member 2

HGNC Previous Symbol

PLI

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000934.4
p.Q458R
c.1373A>G
Surrounding Variants
1 paper
NM_000934.4
p.R465G
c.1393C>G
1 paper
NM_000934.4
p.P451S
c.1351C>T
1 paper
NM_000934.4
p.Q448E
c.1342C>G
2 papers
NM_000934.4
p.L444P
c.1331T>C
1 paper
NM_000934.4
p.E443*
c.1327G>T
1 paper
NM_000934.4
p.R442G
c.1324C>G
3 papers
NM_000934.4
p.R434K
c.1301G>A
1 paper
NM_000934.4
p.V430M
c.1288G>A
1 paper
NM_000934.4
p.P490P
c.1470C>G
1 paper
NM_000934.4
p.F415L
c.1245C>A
1 paper
NM_000934.4
p.F415L
c.1245C>G
1 paper
NM_000934.4
p.F415L
c.1243T>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."