Varaico: Literature-Extracted Genetic Variants

Gene:SESN3
Variant:p.L161insFs

SESN3

35 papers

RefSeq Summary

This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-...

Pfam Domains

PA26aa 39–491UCSCPA26 p53-induced protein (sestrin)

Gene Aliases

HGNC Name

sestrin 3

HGNC Alias Symbols

SEST3; MGC29667

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_144665.4
p.L161insFs
c.481_482ins5
Surrounding Variants
1 paper
NM_144665.4
p.L161M
c.481C>A
1 paper
NM_144665.4
p.L161ins1
c.482_483insACT
1 paper
NM_144665.4
p.K160insFs
c.479_480ins4
1 paper
NM_144665.4
p.L162insFs
c.484_485ins4
1 paper
NM_144665.4
p.L162_A163insFs
c.486_487ins20
1 paper
NM_144665.4
p.A163insFs
c.487_488insCT
1 paper
NM_144665.4
p.A163_H164insFs
c.489_490ins25
1 paper
NM_144665.4
p.R165*
c.493C>T
1 paper
NM_144665.4
p.K171insFs
c.511_512ins31
1 paper
NM_144665.4
p.H173P
c.518A>C
2 papers
NM_144665.4
p.Q175E
c.523C>G
1 paper
NM_144665.4
p.E146K
c.436G>A
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."