Varaico: Literature-Extracted Genetic Variants

SGK3

67 papers

RefSeq Summary

This gene is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. The protein phosphorylates several target proteins and has a role in neutral a...

Pfam Domains

PXaa 38–120UCSCPX domain

Pkinaseaa 162–419UCSCProtein kinase domain

Pkinase_Caa 440–487UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

serum/glucocorticoid regulated kinase family member 3

HGNC Previous Symbol

SGKL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001033578.3

p.R181Q

c.542G>A

Surrounding Variants

1 paper

NM_001033578.3

p.G185*

c.553G>T

1 paper

NM_001033578.3

p.F187V

c.559T>G

1 paper

NM_001033578.3

p.V190L

c.568G>C

6 papers

NM_001033578.3

p.K191N

c.573A>C

6 papers

NM_001033578.3

p.K191N

c.573A>T

1 paper

NM_001033578.3

p.K216_N217ins10

c.646_650ins30

1 paper

NM_001033578.3

p.P221P

c.663G>A

1 paper

NM_001033578.3

p.V239_L240ins11

c.715_719ins33

1 paper

NM_001033578.3

p.L248fs

c.742_743fs

1 paper

NM_001033578.3

p.L248insFs

c.743dupT

1 paper

NM_001033578.3

p.I270V

c.808A>G

1 paper

NM_001033578.3

p.D286H

c.856G>C