sphingosine-1-phosphate phosphatase 2

FLJ39004

Sphingosine-1-phosphate phosphatase 2

Sphingosine-1-phosphatase 2

SPPase2

Spp2

hSPP2

The protein encoded by this gene is a transmembrane protein that degrades the bioactive signaling molecule sphingosine 1-phosphate. The encoded protein is induced during inflammatory responses and has been shown to be downregulated by the microRNA-31 tumor suppressor. Alternative splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2016].

Varaico: Literature-Extracted Genetic Variants

SGPP2

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Alias Symbol