Varaico: Literature-Extracted Genetic Variants

Gene:SH2B3
Variant:p.V35I

SH2B3

633 papers

RefSeq Summary

This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative ...

Pfam Domains

Phe_ZIPaa 25–80UCSCPhenylalanine zipper
SH2aa 364–441UCSCSH2 domain

Gene Aliases

HGNC Name

SH2B adaptor protein 3

HGNC Alias Symbols

LNK; IDDM20

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005475.3
p.V35I
c.103G>A
Surrounding Variants
1 paper
NM_005475.3
p.V35fs
c.103_104fs
1 paper
NM_005475.3
p.A36_L47del12
c.106_140del36
1 paper
NM_005475.3
p.A34V
c.101C>T
1 paper
NM_005475.3
p.A34T
c.100G>A
1 paper
NM_005475.3
p.A34P
c.100G>C
1 paper
NM_005475.3
p.V35_R43delFs
c.104_128del25
4 papers
NM_005475.3
p.A36E
c.107C>A
2 papers
NM_005475.3
p.H33Q
c.99C>A
1 paper
NM_005475.3
p.A37insFs
c.109_110insG
2 papers
NM_005475.3
p.H33Q
c.99C>G
1 paper
NM_005475.3
p.H33P
c.98A>C
1 paper
NM_005475.3
p.A37T
c.109G>A
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