Varaico: Literature-Extracted Genetic Variants

Gene:SH2B3
Variant:p.A37A

SH2B3

633 papers

RefSeq Summary

This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative ...

Pfam Domains

Phe_ZIPaa 25–80UCSCPhenylalanine zipper
SH2aa 364–441UCSCSH2 domain

Gene Aliases

HGNC Name

SH2B adaptor protein 3

HGNC Alias Symbols

LNK; IDDM20

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005475.3
p.A37A
c.111G>C
Surrounding Variants
1 paper
NM_005475.3
p.A37V
c.110C>T
1 paper
NM_005475.3
p.A38T
c.112G>A
1 paper
NM_005475.3
p.A38V
c.113C>T
1 paper
NM_005475.3
p.A38_A42Fs
c.113_125delinsGCCAGCTCGFs
1 paper
NM_005475.3
p.A37T
c.109G>A
4 papers
NM_005475.3
p.A36E
c.107C>A
1 paper
NM_005475.3
p.R39R
c.115C>A
1 paper
NM_005475.3
p.A37insFs
c.109_110insG
1 paper
NM_005475.3
p.A36_L47del12
c.106_140del36
1 paper
NM_005475.3
p.R39R
c.117G>A
1 paper
NM_005475.3
p.E40K
c.118G>A
1 paper
NM_005475.3
p.V35I
c.103G>A
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