Varaico: Literature-Extracted Genetic Variants

Gene:SH2B3
Variant:p.A111P

SH2B3

633 papers

RefSeq Summary

This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative ...

Pfam Domains

Phe_ZIPaa 25–80UCSCPhenylalanine zipper
SH2aa 364–441UCSCSH2 domain

Gene Aliases

HGNC Name

SH2B adaptor protein 3

HGNC Alias Symbols

LNK; IDDM20

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005475.3
p.A111P
c.331G>C
Surrounding Variants
2 papers
NM_005475.3
p.A111T
c.331G>A
1 paper
NM_005475.3
p.A111delFs
c.333delC
1 paper
NM_005475.3
p.A111_P113delFs
c.332_339del8
1 paper
NM_005475.3
p.P113S
c.337C>T
1 paper
NM_005475.3
p.G109S
c.325G>A
1 paper
NM_005475.3
p.G109_P110insG
c.325_329ins3
1 paper
NM_005475.3
p.P108P
c.324C>T
1 paper
NM_005475.3
p.P113P
c.339T>C
1 paper
NM_005475.3
p.P108A
c.322C>G
1 paper
NM_005475.3
p.L115V
c.343C>G
1 paper
NM_005475.3
p.P116_R119insFs
c.347_357dup11
1 paper
NM_005475.3
p.P106L
c.317C>T
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