Varaico: Literature-Extracted Genetic Variants

Gene:SH2B3
Variant:p.H158_T159delins

SH2B3

633 papers

RefSeq Summary

This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative ...

Pfam Domains

Phe_ZIPaa 25–80UCSCPhenylalanine zipper
SH2aa 364–441UCSCSH2 domain

Gene Aliases

HGNC Name

SH2B adaptor protein 3

HGNC Alias Symbols

LNK; IDDM20

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005475.3
p.H158_T159delins
c.473_475delinsCCC
Surrounding Variants
1 paper
NM_005475.3
p.H158P
c.473A>C
1 paper
NM_005475.3
p.A157V
c.470C>T
2 papers
NM_005475.3
p.A156A
c.468G>A
1 paper
NM_005475.3
p.A156V
c.467C>T
1 paper
NM_005475.3
p.A162_P163delFs
c.484_487del4
1 paper
NM_005475.3
p.A161D
c.482C>A
8 papers
NM_005475.3
p.P155L
c.464C>T
1 paper
NM_005475.3
p.A162T
c.484G>A
1 paper
NM_005475.3
p.P163insFs
c.489dupC
1 paper
NM_005475.3
p.A162fs
c.484_485fs
1 paper
NM_005475.3
p.A162Fs
c.486delinsTCFs
1 paper
NM_005475.3
p.E153G
c.458A>G
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