Varaico: Literature-Extracted Genetic Variants

Gene:SH2B3
Variant:p.A161D

SH2B3

633 papers

RefSeq Summary

This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative ...

Pfam Domains

Phe_ZIPaa 25–80UCSCPhenylalanine zipper
SH2aa 364–441UCSCSH2 domain

Gene Aliases

HGNC Name

SH2B adaptor protein 3

HGNC Alias Symbols

LNK; IDDM20

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005475.3
p.A161D
c.482C>A
Surrounding Variants
1 paper
NM_005475.3
p.A162_P163delFs
c.484_487del4
1 paper
NM_005475.3
p.A162T
c.484G>A
1 paper
NM_005475.3
p.P163insFs
c.489dupC
1 paper
NM_005475.3
p.A162fs
c.484_485fs
1 paper
NM_005475.3
p.A162Fs
c.486delinsTCFs
1 paper
NM_005475.3
p.G164delFs
c.492delG
2 papers
NM_005475.3
p.G164R
c.490G>A
2 papers
NM_005475.3
p.G164R
c.490G>C
1 paper
NM_005475.3
p.H158P
c.473A>C
1 paper
NM_005475.3
p.H158_T159delins
c.473_475delinsCCC
1 paper
NM_005475.3
p.T165P
c.493A>C
1 paper
NM_005475.3
p.T165A
c.493A>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."