Varaico: Literature-Extracted Genetic Variants

Gene:SH2B3
Variant:p.A188_R189delFs

SH2B3

633 papers

RefSeq Summary

This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative ...

Pfam Domains

Phe_ZIPaa 25–80UCSCPhenylalanine zipper
SH2aa 364–441UCSCSH2 domain

Gene Aliases

HGNC Name

SH2B adaptor protein 3

HGNC Alias Symbols

LNK; IDDM20

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005475.3
p.A188_R189delFs
c.562_565del4
Surrounding Variants
1 paper
NM_005475.3
p.A188_R189del2
c.562_566del6
1 paper
NM_005475.3
p.R189G
c.565C>G
1 paper
NM_005475.3
p.E190delFs
c.568delG
18 papers
NM_005475.3
p.S186I
c.557G>T
1 paper
NM_005475.3
p.R189Q
c.566G>A
1 paper
NM_005475.3
p.W185*
c.555G>A
1 paper
NM_005475.3
p.W185*
c.554G>A
1 paper
NM_005475.3
p.P184P
c.552C>G
1 paper
NM_005475.3
p.P184P
c.552C>T
1 paper
NM_005475.3
p.P184insFs
c.551_552insG
1 paper
NM_005475.3
p.L183P
c.548T>C
2 papers
NM_005475.3
p.P193_E194del2
c.577_581del6
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