SH3 domain containing GRB2 like 1, endophilin A2

SH3P8

SH3D2B

CNSA1

MGC111371

SH3-domain GRB2-like 1

SH3 domain containing GRB2 like 1

extra 11-19 leukemia fusion

fusion partner of MLL

SH3-containing Grb-2-like 1 protein

SH3-containing protein EEN

SH3 domain GRB2-like 1

endophilin A2

Endophilin-A2

EEN fusion partner of MLL

Endophilin-2

Extra eleven-nineteen leukemia fusion gene protein

SH3 domain protein 2B

SH3 domain-containing GRB2-like protein 1

This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011].

Varaico: Literature-Extracted Genetic Variants

SH3GL1

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Alias Symbols