Varaico: Literature-Extracted Genetic Variants

SHOC2

308 papers

RefSeq Summary

This gene encodes a protein that consists almost entirely of leucine-rich repeats, a domain implicated in protein-protein interactions. The protein may function as a scaffold linking RAS to downstream...

Pfam Domains

LRR_8aa 123–181UCSCLeucine rich repeat

LRR_14aa 205–387UCSCLeucine-rich repeat region

LRR_14aa 442–550UCSCLeucine-rich repeat region

Gene Aliases

HGNC Name

SHOC2 leucine rich repeat scaffold protein

HGNC Alias Symbols

KIAA0862; SOC2; SUR-8; SOC-2; SUR8

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007373.4

p.R74R

c.222G>A

Surrounding Variants

1 paper

NM_007373.4

p.N76I

c.227A>T

1 paper

NM_007373.4

p.T71M

c.212C>T

1 paper

NM_007373.4

p.P79A

c.235C>G

1 paper

NM_007373.4

p.T81A

c.241A>G

1 paper

NM_007373.4

p.R82G

c.244A>G

1 paper

NM_007373.4

p.F66V

c.196T>G

1 paper

NM_007373.4

p.V64G

c.191T>G

2 papers

NM_007373.4

p.G63R

c.187G>A

2 papers

NM_007373.4

p.G63R

c.187G>C

1 paper

NM_007373.4

p.Q61H

c.183A>C

1 paper

NM_007373.4

p.Q61H

c.183A>T

3 papers

NM_007373.4

p.Q61R

c.182A>G