Varaico: Literature-Extracted Genetic Variants

SIGLEC10

69 papers

RefSeq Summary

SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. SIGLEC...

Pfam Domains

V-setaa 24–140UCSCImmunoglobulin V-set domain

I-setaa 255–340UCSCImmunoglobulin I-set domain

Ig_3aa 272–339UCSCImmunoglobulin domain

SIGLECL1_Caa 354–405UCSCSIGLEC family-like protein 1 C-terminal domain

Ig_3aa 362–429UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

sialic acid binding Ig like lectin 10

HGNC Alias Symbols

SIGLEC-10; SLG2; PRO940; MGC126774

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_033130.5

p.Y444Splc

c.1331-1G>A

Surrounding Variants

1 paper

NM_033130.5

p.G479W

c.1435G>T

1 paper

NM_033130.5

p.G432R

c.1294G>C

1 paper

NM_033130.5

p.E481G

c.1442A>G

1 paper

NM_033130.5

p.H426R

c.1277A>G

1 paper

NM_033130.5

p.G421R

c.1261G>C

1 paper

NM_033130.5

p.G421R

c.1261G>A

1 paper

NM_033130.5

p.V417M

c.1249G>A

1 paper

NM_033130.5

p.P407T

c.1219C>A

1 paper

NM_033130.5

p.I534V

c.1600A>G

1 paper

NM_033130.5

p.G373D

c.1118G>A

1 paper

NM_033130.5

p.T559T

c.1677G>A

1 paper

NM_033130.5

p.V340L

c.1018G>T