Varaico: Literature-Extracted Genetic Variants

SIGLEC10

69 papers

RefSeq Summary

SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. SIGLEC...

Pfam Domains

V-setaa 24–140UCSCImmunoglobulin V-set domain

I-setaa 255–340UCSCImmunoglobulin I-set domain

Ig_3aa 272–339UCSCImmunoglobulin domain

SIGLECL1_Caa 354–405UCSCSIGLEC family-like protein 1 C-terminal domain

Ig_3aa 362–429UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

sialic acid binding Ig like lectin 10

HGNC Alias Symbols

SIGLEC-10; SLG2; PRO940; MGC126774

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_033130.5

p.P305T

c.913C>A

Surrounding Variants

1 paper

NM_033130.5

p.K314R

c.941A>G

5 papers

NM_033130.5

p.N292D

c.874A>G

1 paper

NM_033130.5

p.R334Q

c.1001G>A

1 paper

NM_033130.5

p.V340L

c.1018G>T

1 paper

NM_033130.5

p.V340L

c.1018G>C

1 paper

NM_033130.5

p.G269V

c.806G>T

1 paper

NM_033130.5

p.P255L

c.764C>T

1 paper

NM_033130.5

p.P251S

c.751C>T

1 paper

NM_033130.5

p.D248Y

c.742G>T

1 paper

NM_033130.5

p.R247H

c.740G>A

1 paper

NM_033130.5

p.V242I

c.724G>A

1 paper

NM_033130.5

p.G373D

c.1118G>A