Varaico: Literature-Extracted Genetic Variants

SIGLEC10

69 papers

RefSeq Summary

SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. SIGLEC...

Pfam Domains

V-setaa 24–140UCSCImmunoglobulin V-set domain

I-setaa 255–340UCSCImmunoglobulin I-set domain

Ig_3aa 272–339UCSCImmunoglobulin domain

SIGLECL1_Caa 354–405UCSCSIGLEC family-like protein 1 C-terminal domain

Ig_3aa 362–429UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

sialic acid binding Ig like lectin 10

HGNC Alias Symbols

SIGLEC-10; SLG2; PRO940; MGC126774

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_033130.5

p.T193M

c.578C>T

Surrounding Variants

1 paper

NM_033130.5

p.T193R

c.578C>G

1 paper

NM_033130.5

p.K191R

c.572A>G

1 paper

NM_033130.5

p.Q188L

c.563A>T

1 paper

NM_033130.5

p.P204S

c.610C>T

1 paper

NM_033130.5

p.P176S

c.526C>T

1 paper

NM_033130.5

p.P175A

c.523C>G

1 paper

NM_033130.5

p.D212N

c.634G>A

1 paper

NM_033130.5

p.E172K

c.514G>A

1 paper

NM_033130.5

p.E171K

c.511G>A

1 paper

NM_033130.5

p.T161M

c.482C>T

1 paper

NM_033130.5

p.A226T

c.676G>A

1 paper

NM_033130.5

p.V160L

c.478G>T