Varaico: Literature-Extracted Genetic Variants

SIGLEC10

69 papers

RefSeq Summary

SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. SIGLEC...

Pfam Domains

V-setaa 24–140UCSCImmunoglobulin V-set domain

I-setaa 255–340UCSCImmunoglobulin I-set domain

Ig_3aa 272–339UCSCImmunoglobulin domain

SIGLECL1_Caa 354–405UCSCSIGLEC family-like protein 1 C-terminal domain

Ig_3aa 362–429UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

sialic acid binding Ig like lectin 10

HGNC Alias Symbols

SIGLEC-10; SLG2; PRO940; MGC126774

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_033130.5

p.M1T

c.2T>C

Surrounding Variants

1 paper

NM_033130.5

p.M1I

c.3G>T

1 paper

NM_033130.5

p.M1I

c.3G>C

1 paper

NM_033130.5

p.G12C

c.34G>T

1 paper

NM_033130.5

p.G12V

c.35G>T

2 papers

NM_033130.5

p.G12D

c.35G>A

1 paper

NM_033130.5

p.Y45C

c.134A>G

1 paper

NM_033130.5

p.R47Q

c.140G>A

1 paper

NM_033130.5

p.E66Q

c.196G>C

1 paper

NM_033130.5

p.T75K

c.224C>A

1 paper

NM_033130.5

p.N76Y

c.226A>T

1 paper

NM_033130.5

p.R80*

c.238C>T

1 paper

NM_033130.5

p.R80Q

c.239G>A