Varaico: Literature-Extracted Genetic Variants

SIGMAR1

169 papers

RefSeq Summary

This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular func...

Pfam Domains

ERG2_Sigma1Raa 13–129UCSCERG2 and Sigma1 receptor like protein

ERG2_Sigma1Raa 13–217UCSCERG2 and Sigma1 receptor like protein

Gene Aliases

HGNC Name

sigma non-opioid intracellular receptor 1

HGNC Previous Symbol

OPRS1

Papers

RefSeq ID

Protein change

DNA change

1–12 of 139 variants

42 papers

NM_005866.4

p.E102Q

c.304G>C

18 papers

NM_005866.4

p.Q2P

c.5A>C

15 papers

NM_005866.4

p.G51Splc

c.151+1G>T

13 papers

NM_005866.4

p.E150K

c.448G>A

12 papers

NM_005866.4

p.L95fs

c.283_284fs

11 papers

NM_005866.4

p.L95insFs

c.283dupC

11 papers

NM_005866.4

p.E138Q

c.412G>C

11 papers

NM_005866.4

p.R208W

c.622C>T

10 papers

NM_005866.4

p.L65Q

c.194T>A

9 papers

NM_005866.4

p.N167I

c.500A>T

8 papers

NM_005866.4

p.A187_S192delFs

c.561_576del16

7 papers

NM_005866.4

p.W169R

c.505T>A