Varaico: Literature-Extracted Genetic Variants

SIGMAR1

169 papers

RefSeq Summary

This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular func...

Pfam Domains

ERG2_Sigma1Raa 13–129UCSCERG2 and Sigma1 receptor like protein

ERG2_Sigma1Raa 13–217UCSCERG2 and Sigma1 receptor like protein

Gene Aliases

HGNC Name

sigma non-opioid intracellular receptor 1

HGNC Previous Symbol

OPRS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005866.4

p.T202insFs

c.604_605insAG

Surrounding Variants

1 paper

NM_005866.4

p.R204C

c.610C>T

1 paper

NM_005866.4

p.R204H

c.611G>A

1 paper

NM_005866.4

p.L199F

c.595C>T

1 paper

NM_005866.4

p.Y206_A207insFs

c.618_619insAG

1 paper

NM_005866.4

p.L197F

c.589C>T

11 papers

NM_005866.4

p.R208W

c.622C>T

1 paper

NM_005866.4

p.D195E

c.585C>G

1 paper

NM_005866.4

p.G209D

c.626G>A

1 paper

NM_005866.4

p.Q194H

c.582G>T

1 paper

NM_005866.4

p.Q194H

c.582G>C

1 paper

NM_005866.4

p.L210fs

c.628_629fs

1 paper

NM_005866.4

p.L210R

c.629T>G