Varaico: Literature-Extracted Genetic Variants

SIGMAR1

169 papers

RefSeq Summary

This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular func...

Pfam Domains

ERG2_Sigma1Raa 13–129UCSCERG2 and Sigma1 receptor like protein

ERG2_Sigma1Raa 13–217UCSCERG2 and Sigma1 receptor like protein

Gene Aliases

HGNC Name

sigma non-opioid intracellular receptor 1

HGNC Previous Symbol

OPRS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_005866.4

p.A185P

c.553G>C

Surrounding Variants

1 paper

NM_005866.4

p.A185T

c.553G>A

1 paper

NM_005866.4

p.A185V

c.554C>T

1 paper

NM_005866.4

p.L186_A187insFs

c.558_559insC

1 paper

NM_005866.4

p.A187T

c.559G>A

1 paper

NM_005866.4

p.A183T

c.547G>A

1 paper

NM_005866.4

p.A187V

c.560C>T

5 papers

NM_005866.4

p.L182P

c.545T>C

1 paper

NM_005866.4

p.D188N

c.562G>A

4 papers

NM_005866.4

p.D188fs

c.562_563fs

1 paper

NM_005866.4

p.S180F

c.539C>T

1 paper

NM_005866.4

p.V190L

c.568G>C

1 paper

NM_005866.4

p.V177I

c.529G>A