Varaico: Literature-Extracted Genetic Variants

SIGMAR1

169 papers

RefSeq Summary

This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular func...

Pfam Domains

ERG2_Sigma1Raa 13–129UCSCERG2 and Sigma1 receptor like protein

ERG2_Sigma1Raa 13–217UCSCERG2 and Sigma1 receptor like protein

Gene Aliases

HGNC Name

sigma non-opioid intracellular receptor 1

HGNC Previous Symbol

OPRS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_147157.3

p.T137A

c.409A>G

Surrounding Variants

9 papers

NM_005866.4

p.N167I

c.500A>T

4 papers

NM_005866.4

p.W169R

c.505T>C

7 papers

NM_005866.4

p.W169R

c.505T>A

1 paper

NM_147157.3

p.G134R

c.400G>A

1 paper

NM_005866.4

p.E172G

c.515A>G

1 paper

NM_005866.4

p.E172D

c.516G>T

1 paper

NM_005866.4

p.E172D

c.516G>C

1 paper

NM_005866.4

p.G174S

c.520G>A

1 paper

NM_005866.4

p.G174V

c.521G>T

1 paper

NM_005866.4

p.R175W

c.523C>T

1 paper

NM_005866.4

p.V177I

c.529G>A

1 paper

NM_005866.4

p.P156_G157delFs

c.468_469delCA