Varaico: Literature-Extracted Genetic Variants

SIGMAR1

169 papers

RefSeq Summary

This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular func...

Pfam Domains

ERG2_Sigma1Raa 13–129UCSCERG2 and Sigma1 receptor like protein

ERG2_Sigma1Raa 13–217UCSCERG2 and Sigma1 receptor like protein

Gene Aliases

HGNC Name

sigma non-opioid intracellular receptor 1

HGNC Previous Symbol

OPRS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005866.4

p.D126G

c.377A>G

Surrounding Variants

1 paper

NM_005866.4

p.D126A

c.377A>C

1 paper

NM_005866.4

p.D126N

c.376G>A

4 papers

NM_005866.4

p.I128F

c.382A>T

1 paper

NM_005866.4

p.E123D

c.369G>C

1 paper

NM_005866.4

p.W121*

c.363G>A

1 paper

NM_005866.4

p.G131_T132insFs

c.391_394dup4

1 paper

NM_005866.4

p.G118V

c.353G>T

11 papers

NM_005866.4

p.E138Q

c.412G>C

4 papers

NM_005866.4

p.E138K

c.412G>A

1 paper

NM_005866.4

p.G139V

c.416G>T

3 papers

NM_005866.4

p.G118Splc

c.352+1G>A

1 paper

NM_005866.4

p.S117L

c.350C>T