Varaico: Literature-Extracted Genetic Variants

SIGMAR1

169 papers

RefSeq Summary

This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular func...

Pfam Domains

ERG2_Sigma1Raa 13–129UCSCERG2 and Sigma1 receptor like protein

ERG2_Sigma1Raa 13–217UCSCERG2 and Sigma1 receptor like protein

Gene Aliases

HGNC Name

sigma non-opioid intracellular receptor 1

HGNC Previous Symbol

OPRS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

42 papers

NM_005866.4

p.E102Q

c.304G>C

Surrounding Variants

1 paper

NM_005866.4

p.E102A

c.305A>C

1 paper

NM_005866.4

p.E102D

c.306G>T

1 paper

NM_005866.4

p.E102D

c.306G>C

1 paper

NM_005866.4

p.Y103*

c.309T>G

1 paper

NM_005866.4

p.Y103*

c.309T>A

1 paper

NM_005866.4

p.S99S

c.297G>T

1 paper

NM_005866.4

p.S99L

c.296C>T

1 paper

NM_005866.4

p.L96P

c.287T>C

12 papers

NM_005866.4

p.L95fs

c.283_284fs

11 papers

NM_005866.4

p.L95insFs

c.283dupC

3 papers

NM_005866.4

p.L95fs

c.283_284fs

1 paper

NM_005866.4

p.L95F

c.283C>T